Efficacy of Ozone Gel, Doxycycline Saturated Chitosan Dressing Versus Alveogyl

Minia University

Status: Completed

Conditions: Dry Socket; Osteitis

Treatments: Drug: Ozone gel; Drug: doxycycline hyclate saturated chitosan dressing

Study type: Interventional

Funder types: Other

Identifiers

NCT05875506

713

Details and patient eligibility

About

Efficacy of ozone gel, doxycycline saturated chitosan dressing versus Alveogyl in pain alleviation and healing of alveolar osteitis in diabetic patients

Enrollment: 60 patients

Sex: All

Ages: 20 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients over 20 years and under 60 years of age
• DM controlled by medication, presented to outpatient clinic with signs and symptoms of dry socket
• Only participant that are willing to control and record blood glucose level throughout the study period

Exclusion criteria

• Patients with any significant medical condition (besides DM)
• Alcoholic individuals
• Patients on drugs that affect the central nervous systems
• Patients who reported the use of drugs that might interfere with pain sensitivity
• Pregnant and lactating women
• Hypersensitivity to local anesthetics

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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60 participants in 3 patient groups

Ozone gel

Experimental group

Description:

(Ozene; Premier Research Labs, lp, 3500-b Wadley pl, Austin, TX, USA. 78728)

Treatment:

Drug: Ozone gel

doxycycline hyclate saturated chitosan dressing

Experimental group

Description:

doxycycline hyclate ( Atridox 10% Tolmar Inc, USA) saturated chitosan dressing (HHD) HemCon dental dressing Pro ( Tricol Biomedical, Inc. USA)

Treatment:

Drug: doxycycline hyclate saturated chitosan dressing

Alveogyl paste

Active Comparator group

Description:

Alveogyl paste ( Septodont, inc, france)

Treatment:

Drug: doxycycline hyclate saturated chitosan dressing

Drug: Ozone gel