Efficacy of Pilocarpine As a Secretagogue Versus Artificial Tears for the Treatment of Dry Eye

Al-Azhar University

Status: Completed

Conditions: Dry Eye Disease (DED)

Treatments: Drug: Pilocarpine; Drug: artificial tears

Study type: Interventional

Funder types: Other

Identifiers

NCT06752278

Pilocarpine and Dry Eye

Details and patient eligibility

About

Management approaches for dry eye disease (DED) typically start with low-risk, easily accessible, patient-applied therapies like artificial tears for early-stage disease. As the condition worsens, treatment progresses to more advanced therapies for severe forms of DED. This study aims to compare the effectiveness and safety of pilocarpine as a secretagogue versus artificial tears in the treatment of dry eye disease. Our goal is to provide reliable, high-quality evidence regarding the efficacy of secretagogues, thereby contributing to the development of recommendations that aid clinicians in their decision-making process

Enrollment: 40 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients diagnosed with DED

Exclusion criteria

• Previous Occular surgery.
• Refuse to particupate.
• Patients with sjogren syndrome

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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40 participants in 2 patient groups

pilocarpine group

Active Comparator group

Treatment:

Drug: Pilocarpine

artificial tears group

Active Comparator group

Treatment:

Drug: artificial tears