Efficacy of Platelet-Rich Plasma Injection in Dry Eye Syndrome (ReLIPSSO)

Centre Hospitalier Universitaire de Nice

Status: Enrolling

Conditions: Dry Eye Syndromes; Severe Dry Eye Syndromes

Treatments: Other: injections of Platelet-Rich Plasma in lacrimal gland

Study type: Interventional

Funder types: Other

Identifiers

NCT06831253

24-AOIP-02

IDRCB (Other Identifier)

Details and patient eligibility

About

The investigatror wants to show the efficacy of Platelet-Rich Plasma injection in lacrimal gland to restore the lacrimal secretion in patients presenting aqueous deficiency reponsible for severe dry eye syndrome.

Full description

injections in lacrimal gland four times during the study for each patient

Enrollment: 20 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Platelet counts, and clotting factors in the standarts
• Presenting with severe dry keratoconjunctivitis diagnosed by an ophthalmologist

Exclusion criteria

• Patients with significant fibrosis of the conjunctival portion of the lacrimal gland
• Patients with complete stenosis of both lacrimal meatus in the treated eye

Trial design

Primary purpose: Treatment

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

---

20 participants in 1 patient group

Injection of Platelet-Rich Plasma (PRP)

Experimental group

Treatment:

Other: injections of Platelet-Rich Plasma in lacrimal gland