Efficacy of Popliteal Nerve Blocks With and Without Dexamethasone on the Duration of Analgesia for Foot & Ankle Surgery

Cedars-Sinai Medical Center

Status and phase: Completed; Phase 4

Conditions: Foot and Ankle Procedures

Treatments: Drug: Saline; Drug: Dexamethasone

Study type: Interventional

Funder types: Other

Identifiers

NCT01975285

Pro00032547

Details and patient eligibility

About

The purpose of this research study to evaluate the effects of dexamethasone as an addition to peripheral nerve block (Put the nerve to sleep with Bupivacaine a numbing medication) on length of pain relief (analgesia), postoperative narcotic (opioids) requirements, pain scores, and patient satisfaction after foot and ankle procedures.

Enrollment: 60 patients

Sex: All

Ages: 18 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 60 patients (30 per group) undergoing foot and ankle procedures
• Willingness and ability to sign an informed consent document
• No allergies to anesthetic or analgesic medications
• American Society of Anesthesiologists (ASA)physical status Class I - III
• Aged 18-90 years,either sex

Exclusion criteria

• Refusal to participate in the study
• Age<18 or> 90 years -
• Contraindications to regional blockage including but not limited to:
• Patient refusal to regional blockade
• Infection at the site of needle insertion
• Systemic infection
• Bleeding diathesis or coagulopathy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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60 participants in 2 patient groups, including a placebo group

Dexamethasone group

Active Comparator group

Description:

Dexamethasone 4mg(1 ml) per 20cc

Treatment:

Drug: Dexamethasone

Saline group

Placebo Comparator group

Description:

Saline 1 ml per 20cc

Treatment:

Drug: Saline