Efficacy of Pre-operative Oral Pregabalin in Ambulatory Inguinal Hernia Repair for Post Operative Pain

University of Malaya

Status and phase: Unknown; Phase 3

Conditions: Postoperative Pain; Inguinal Hernia

Treatments: Drug: Pregabalin

Study type: Interventional

Funder types: Other

Identifiers

NCT01450345

toh2c79@Pregabalin

Details and patient eligibility

About

The study carry out is to determine whether the use of oral pregabalin premedication to assess the analgesic efficacy, opiod sparing, adverse effect and clinical value in post-operative pain management.

Enrollment: 72 estimated patients

Sex: All

Ages: 12 to 75 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Clinical diagnosis of inguinal hernia
• Patient undergo operation under daycare basis
• ASA I-II
• Written consent

Exclusion criteria

• ASA > II
• Allergic reaction against gabapentin and/or pregabalin
• History of recurrent hernia repair.
• Patient who has taken analgesia prior to the surgery
• Liver failure
• Renal failure
• Pregnancy

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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72 participants in 1 patient group

Pregabalin Group

Experimental group

Description:

The patient under Group P will be serving with 150 mg of oral Pregabalin 1 to 2 hours prior to induction.

Treatment:

Drug: Pregabalin