Efficacy of Preoperative Enema in the Prevention of Catheter Dysfunction in Peritoneal Dialysis

Air Force Military Medical University of People's Liberation Army

Status: Not yet enrolling

Conditions: Peritoneal Dialysis Access Failure

Treatments: Procedure: enema

Study type: Interventional

Funder types: Other

Identifiers

NCT05258552

enema for PD

Details and patient eligibility

About

A prospective, randomized, controlled study was conducted to identify patients with end-stage renal disease who required open peritoneal dialysis catheterization, preoperative enema or no enema was used to evaluate the efficacy and safety of reducing catheter dysfunction.

Full description

A prospective, randomized, controlled study was conducted to identify patients with end-stage renal disease who required open peritoneal dialysis catheterization, preoperative enema or no enema was used to evaluate the efficacy and safety of reducing catheter dysfunction. All the patients were divided into two groups: preoperative enema group and no intervention group. The peritoneal dialysis malfuction were observed.

Enrollment: 136 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age ≥18;
• Maintenance peritoneal dialysis treatment is required for end-stage Renal Disease;
• First-time open surgeon peritoneal dialysis catheterization patient;
• Only straight double-cuff Tenckhoff dialysis catheters were used.
• Willing to participate in this study and sign informed consent form.

Exclusion criteria

• peritoneal dialysis contraindication;
• Enema contraindication;
• Patients refuse enema;
• Expected survival time < 3 months;
• Catharsis such as Senna Leaf and lactulose used before operation or colonic dialysis and enema used 3 days before operation.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

---

136 participants in 2 patient groups

Enema group

Experimental group

Treatment:

Procedure: enema

Control group

No Intervention group