Efficacy of Prokinetics With Split Dose of PEG in Morning Colonoscopic Bowel Preparation (PSPEG)

Inje University

Status and phase: Completed; Phase 3

Conditions: Bowel Preparation; Colonoscopy

Treatments: Drug: itopride

Study type: Interventional

Funder types: Other

Identifiers

NCT01513096

GI-201201

Details and patient eligibility

About

In bowel preparation using split dose PEG, various adjuncts to colonic cleansing were proposed to improve colonic preparation cleansing. Prokinetics, as an adjunct, was included in a few studies. The investigators study was to show that sufficient dosage of prokinetics added to split dose of PEG improves the state of bowel preparation.

Full description

This was a randomized, prospective, endoscopist-blinded clinical trial in which the efficacy of prokinetics coadministrated with split dose PEG on the bowel cleansing was inspected.

Endoscopists, who were blinded to the study group of the patient, immediately completed the Ottawa scale and the fluidity scale after procedure

Enrollment: 152 patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patient who are scheduled for colonoscopy

Exclusion criteria

• pregnancy,
• breast feeding,
• known or suspected bowel obstruction, and
• known allergy to PEG or Itopride ,
• presence of severe illness(renal failure, congestive heart failure, liver failure,), and
• refusal of consent to participate in the study

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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152 participants in 2 patient groups

Split-dose PEG

No Intervention group

Description:

Bowel preparation using split dose PEG without prokinetics

Split dose PEG with prokinetics

Active Comparator group

Description:

Bowel preparation using split-dose PEG with prokinetics

Treatment:

Drug: itopride