Efficacy of Prophylactic Glycerin Suppositories for Feeding Intolerance in Very Low Birth Weight Preterm Infants: a Randomized Trial

King Faisal Specialist Hospital & Research Center

Status: Terminated

Conditions: Infant, Very Low Birth Weight

Treatments: Drug: Glycerin suppositories

Study type: Interventional

Funder types: Other

Identifiers

NCT01799629

2121 110

Details and patient eligibility

About

To evaluate the efficacy of prophylactic glycerin suppositories will accelerate the elimination of meconium from the large intestine and thus reduce the incidence of feeding intolerance in very low birth weight (VLBW) infants

Enrollment: 220 patients

Sex: All

Ages: Under 1 month old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Preterm infants with birth weight < 1250g.
2. Inborn or outborn infants
3. Less than 72 hours of age.

Exclusion criteria

1. Congenital malformations.
2. Acute abdomen needing surgical intervention.
3. Severity of illness such that death is likely in the first few days after birth.
4. Inability to get the parental consent.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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220 participants in 2 patient groups

Intervention

Experimental group

Description:

Intervention group will receive the glycerin suppository

Treatment:

Drug: Glycerin suppositories

Control

No Intervention group

Description:

Normal care