Efficacy of Repyflec Cognitive Remediation Group Training in Schizophrenia

Fundació Sant Joan de Déu

Status and phase

Completed

Phase 4

Conditions

Indication for Modification of Patient Cognitive Status

Treatments

Behavioral: Repyflec cognitive remediation training

Study type

Interventional

Funder types

Other

Identifiers

NCT01279070

REPYFLEC Clinical Trial

Details and patient eligibility

About

The purpose of this study was to develop an integrative intervention for schizophrenia taking into account previous efficacious therapies. Thus, our aim was to evaluate the efficacy of our cognitive remediation group training: Problem Solving and Cognitive Flexibility training (REPYFLEC), focused to improve neurocognition and functioning in schizophrenia patients. We hypothesized that training executive function and metacognition would allow us to achieve improvements in neurocognition, functioning and psychiatric symptoms of patients with schizophrenia.

Enrollment

62 patients

Sex

All

Ages

18 to 60 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

Diagnosis of schizophrenia or schizoaffective disorder
More than 2 years illness duration
Literate
Mini Mental Status Examination score over 24
Global Assessment of Functioning scores between 40 and 70

Exclusion criteria

Current acute illness exacerbation
Mental Retardation
Neurological disorder which impairs cognition
Currently participating in social skills training or cognitive remediation
Change of antipsychotic medication one month before the trial or during the 40 study weeks
Diagnosis of alcohol or drug dependence within 6 months of trial commencement.