Efficacy of rTMS in the Treatment of Patients With Migraine

Taipei Veterans General Hospital

Status: Unknown

Conditions: Migraine

Treatments: Device: Repetitive Transcranial Magnetic Stimulation (rTMS)

Study type: Interventional

Funder types: Other

Identifiers

NCT00316979

rTMS_Migraine_VGHTPE

Details and patient eligibility

About

Migraine is a condition thought to be related to cortical hyperexcitability. Repetitive transcranial magnetic stimulation (rTMS) can modulate the cortical excitability by means of long-term potentiation or long-term depression. This study will will test the safety and efficacy of rTMS in the treatment of patients with Migraine.

Enrollment: 80 estimated patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Age of 18-65 years
• Diagnosed as migraine (with or without aura)
• More than 4 attacks per month for at least 3 months prior to study
• No preventive medication used
• Must be able to sign permit

Exclusion criteria

• History of seizure or family history of seizures
• Women in pregnancy or breast-feeding
• Patient with medication overuse
• Patient with other medical, psychologic, or surgical illness
• Patient under preventive medications
• Prior rTMS examination one month within

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind