Efficacy of Serratus Anterior Plane Block Mastectomy

doaa rashwan

Status: Completed

Conditions: Postoperative Complications; Postoperative Pain

Treatments: Procedure: serratus anterior plan block

Study type: Interventional

Funder types: Other

Identifiers

NCT03944759

FMBSURECS/30042019/Ali

Details and patient eligibility

About

Breast cancer is the main common cancer among females. . Inadequate control of pain may later develop into chronic pain syndrome (paraesthesias, phantom breast pain, and intercostobrachial neuralgia) in 25-40% of the patients .

Full description

The aim of this study is to compare the efficacy of ultrasound-guided serratus anterior plane block with bupivacaine/ magnesium versus bupivacaine/ nalbuphine in breast cancer surgery.

Patients and methods nclusion criteria:

-ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion criteria:

• Patient refusal
• Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)
• Allergy to the drugs used in the study
• Chronic pain therapy,
• BMI more than 30 kg/m2

Enrollment: 40 patients

Sex: Female

Ages: 25 to 60 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• ASA I and II female patients, age 25-60 undergoing breast cancer surgery

Exclusion criteria

• -Patient refusal
• Contraindications for regional blocks (eg. Infection at the injection site, coagulopathy)
• Allergy to the drugs used in the study
• Chronic pain therapy,
• BMI more than 30 kg/m2

Trial design

Primary purpose: Other

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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40 participants in 2 patient groups

GBM:( bupivacaine/magnesium sulphate)

Active Comparator group

Description:

serratus plane block will performed in the supine position under strict aseptic conditions before induction of anesthesia. GBM:( bupivacaine/magnesium sulphate): will receive bupivacaine 30 ml 0.25 and 500 mg magnesium sulphate

Treatment:

Procedure: serratus anterior plan block

GBN: ( bupivacaine/nalpuphin)

Active Comparator group

Description:

serratus plane block will performed in the supine position under strict aseptic conditions before induction of anesthesia.. ( bupivacaine/nalpuphin):received bupivacaine 30 ml 0.25 % and nalpuphine 0.2mg/kg.

Treatment:

Procedure: serratus anterior plan block