Efficacy of Social Cognition Training in Schizophrenia

VA Connecticut Healthcare System

Status: Completed

Conditions: Schizophrenia

Treatments: Behavioral: WLC; Behavioral: Social Cognition Interaction Training

Study type: Interventional

Funder types: Other U.S. Federal agency

Identifiers

NCT00587561

D4628W

JMF0005

Details and patient eligibility

About

The term social cognition refers to how social information is processed. Individuals with schizophrenia and schizoaffective disorder have been shown to have significant deficits in social cognition. Moreover, it has been speculated that these deficits may in turn have a negative impact on their overall functioning. Behavioral interventions targeting social cognition are just beginning to emerge, and there is a need to evaluate their efficacy.

Objectives:

This is a small trial evaluating the efficacy of social cognition interaction training (SCIT) an experimental behavioral treatment for improving social cognition in schizophrenia.

Research Design and Methodology:

Approximately 48 participants with schizophrenia-spectrum disorders will be randomized into one of two conditions: 1) a 20 to 24 session manualized social cognition interaction training group (SCIT), or 2) wait-list control. Pre-and post-group therapy assessments of symptoms, social cognition, basic cognition, and community function will be conducted. Data obtained from this study will allow us to determine the efficacy of SCIT training in improving symptom, cognitive, and functional measures.

Enrollment: 51 patients

Sex: All

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• diagnosis of schizophrenia or schizoaffective disorder
• Age between 18 and 65
• minimum of 30 days since discharge from last hospitalization
• minimum of 30 days since last change in psychiatric medications
• no housing changes in the past 30 days

Exclusion criteria

• current diagnosis of alcohol or substance abuse/dependence
• history of brain trauma or neurological disease
• mental retardation or developmental disability
• auditory or visual impairment that would interfere with study procedures

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Crossover Assignment

Masking: None (Open label)

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51 participants in 2 patient groups

1 Social Cognition Interaction Training

Experimental group

Description:

Will receive 20-26 sessions of a manualized group treatment called Social Cognition Interaction Training

Treatment:

Behavioral: Social Cognition Interaction Training

2 Wait List Control

Other group

Description:

Wait list control; 6 months of treatment as usual followed by Social Cognition Interaction Training group

Treatment:

Behavioral: WLC