ClinicalTrials.Veeva

Menu

Efficacy of Standardized-propolis Extract (EPP-AF®) Gel Formulation as Buccal Antiseptic

U

University of Sao Paulo

Status and phase

Completed
Phase 3

Conditions

Stomatitis, Denture
Candidiasis, Oral

Treatments

Other: Propolis
Drug: Miconazole

Study type

Interventional

Funder types

Other

Identifiers

NCT02818803
1057529

Details and patient eligibility

About

The purpose of this study is to evaluate the efficacy and safety of propolis on the treatment of oral candidiasis, more specifically denture stomatitis. Half of participants will receive a standardized-propolis (EPP-AF®) gel formulation while the other half will receive miconazole gel, both for oral use.

Enrollment

40 patients

Sex

All

Ages

60+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Elderly patients with denture stomatitis

Exclusion criteria

  • Recent use of anti fungals or antibiotics(2 months or less), dementia

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

40 participants in 2 patient groups

Propolis
Experimental group
Description:
Standardized-propolis extract (EPP-AF®) oral gel formulation, 3 times a day, for 14 days
Treatment:
Other: Propolis
Miconazole
Active Comparator group
Description:
Miconazole 20mg/g oral gel,3 times a day, for 14 days
Treatment:
Drug: Miconazole

Trial contacts and locations

2

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems