Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans

Julieta María Méndez Romero

Status: Completed

Conditions: Dental Plaque; Streptococcus, Other Specified Group

Treatments: Other: CHLORHEXIDINE MOUTHWASH; Other: CARICA PAPAYA MOUTHWASH

Study type: Interventional

Funder types: Other

Identifiers

NCT04485520

00140

Details and patient eligibility

About

Papaya has effects on oral pathogenic microorganisms, it also has anticoagulant quality, amebicidal action, antimicrobial, bacteriostatic and antifungal activity on different bacteria, especially on Streptococcus mutans, this can be exploited in the dental area. The objective of the study was to determine the efficacy of Carica Papaya peel extract (suckling) as an inhibitor of Streptococcus Mutans in students of the dental faculty of the National University of Caaguazú in 2018.

Full description

Specific objectives

• To determine the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on Streptococcus Mutans by age and sex grouping.
• To quantify the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on the growth of Streptococcus Mutans before, at 10 minutes and 8 days of use in the experimental group.
• Quantify the inhibition of 0.12% Chlorhexidine Gluconate on the growth of Streptococcus Mutans before, after 10 minutes and 8 days of use in the control group.
• Compare the count of Colony Forming Units (CFU) between both groups.

Enrollment: 40 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Participants that signed the informed consent

Exclusion criteria

• allergic to carica papaya
• ongoing medical or dental treatment that could interfere with the results.

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups

Carica Papaya extract

Experimental group

Description:

Carica Papaya at 3%

Treatment:

Other: CARICA PAPAYA MOUTHWASH

Chlorhexidine

Active Comparator group

Description:

0.12% chlorhexidine mouthwash formulation (commercially available)

Treatment:

Other: CHLORHEXIDINE MOUTHWASH