Efficacy of the Memory Motivation (MEMO) Web Application Training (MeMo)

Innovation Alzheimer

Status: Completed

Conditions: Neurocognitive Disorders

Treatments: Other: Control group; Device: MeMo web application

Study type: Interventional

Funder types: Other

Identifiers

NCT04142801

2016-A00879-42

Details and patient eligibility

About

Memory, attentional, and behavioural symptoms are the clinical hallmarks of Neurocognitive disorders (NCD) such as Alzheimer's disease and related disorders. The World Health Organisation (WHO) guidelines for risk reduction of cognitive decline and dementia indicate that Cognitive training may be offered to older adults with normal cognition and with mild cognitive impairment to reduce the risk of cognitive decline and/or dementia. The use of Information and Communication Technologies (ICT) in the health domain is progressively expanding. The Alzheimer Innovation Association have developed MeMo (Memory Motivation) a free web application that can be used at home by patients.

The objective of the present study was to assess the effectiveness of employing the MeMo platform on cognitive performance in patients suffering from NCD.

Full description

The objective of this study is to evaluate the effectiveness of the MeMo cognitive training exercise platform in patients suffering from neurocognitive disorders. These exercises ,have been developed by the association Innovation Alzheimer and the CoBTeK research team, located with the Nice memory Center at the Institut Claude Pompidou. MeMo can be used freely at home by patients. More specifically, it is a randomized controlled study that aims to compare the evolution of activities cognition and behavior between patients not using these exercises, and patients using these exercises for 12 weeks, 4 sessions per week.

Enrollment: 49 patients

Sex: All

Ages: 60 to 90 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Outpatient consulting the Memory center
• older than 60 years old
• Mini Mental State examination score (MMSE) between 16 and 28 / 30
• met the DSM 5 diagnoses of mild neurocognitive disorders (mild NCD) or major neurocognitive disorders (Major NCD).

Exclusion criteria

• Patients not able to read and write French
• presence of a hearing or major visual impairment
• a history of premorbid mental retardation
• had already used the MeMo application
• were presently involved in structured memory training activities.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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49 participants in 2 patient groups, including a placebo group

MeMo group

Experimental group

Description:

MeMo group: experimental: regular use at home of the Memo web application In the Memo group patients were instructed on how to use the application, and allowed to train for 12 weeks. It was also explained that this training needed to be done regularly on a basis of 4 sessions of 30 minutes each per week.

Treatment:

Device: MeMo web application

Control group

Placebo Comparator group

Description:

Regular follow up at the memory center without cognitive training

Treatment:

Other: Control group