Efficacy of Various Treatments for Acute Acoustic Trauma.

Medical Corps, Israel Defense Force

Status: Unknown

Conditions: Acute Acoustic Trauma

Treatments: Other: No intervention - retrospective study

Study type: Observational

Funder types: Other

Identifiers

NCT04482998

2131-2020

Details and patient eligibility

About

Acute acoustic trauma is a growing concern in the IDF. there is currently no accepted treatment. The present retrospective study is intended to evaluate the efficacy of different treatment modalities in the IDF between 01/01/2010 and 15/06/2020.

Enrollment: 250 estimated patients

Sex: All

Ages: 18 to 40 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Subjects diagnosed with acute acoustic trauma.
• Hearing exam performed at least 24 hours after acute acoustic trauma.
• There was a reduction of at least 30dB in the 3,000-8,000 Hz frequency range in the first hearing exam performed.

Exclusion criteria

• A known hearing impairment prior to acute acoustic trauma.
• Subjects lost from follow up.
• Another diagnosis is more likely than hearing loss due to acute acoustic trauma.

Trial design

250 participants in 8 patient groups

Steroids only - early

Description:

treatment was initiated within 7 days of acoustic trauma.

Treatment:

Other: No intervention - retrospective study

Early combined steroid and hyperbaric oxygen therapy

Description:

treatment was initiated within 7 days of acoustic trauma.

Treatment:

Other: No intervention - retrospective study

Delayed combined steroid and hyperbaric oxygen therapy

Description:

treatment was initiated after 7 days of acoustic trauma.

Treatment:

Other: No intervention - retrospective study

Early sequential steroid followed by HBO therapy

Description:

treatment was initiated within 7 days of acoustic trauma.

Treatment:

Other: No intervention - retrospective study

Delayed sequential steroid followed by HBO therapy

Description:

treatment was initiated after 7 days of acoustic trauma.

Treatment:

Other: No intervention - retrospective study

Hyperbaric oxygen therapy only

Treatment:

Other: No intervention - retrospective study

No treatment

Treatment:

Other: No intervention - retrospective study

Steroid only - delayed

Description:

treatment was initiated after 7 days of acoustic trauma.

Treatment:

Other: No intervention - retrospective study