Efficacy of Xenograft Alone or Mixed With Arginyl-Glycyl-Aspartic Acid (RGD) in Horizontal Ridge Augmentation With Split-crest Technique for Implant Placement

Al-Azhar University

Status: Enrolling

Conditions: Implant Dentistry

Treatments: Procedure: Split crest technique; Drug: Xenograft; Drug: RGD

Study type: Interventional

Funder types: Other

Identifiers

NCT06585852

RGD in Ridge splitting

Details and patient eligibility

About

The aim of the present study is to evaluate the efficacy of xenograft alone or xenograft mixed with Arginylglycylaspartic acid (RGD) , in horizontal ridge augmentation with split-crest technique, for implant placement.

Full description

A comparative study for ridge augmentation procedure, With two groups. First group underwent a surgical ridge splitting procedure with ultrasonic bone surgery and grafting with Xenograft alone and implant placement. Second group underwent a surgical ridge splitting procedure with ultrasonic bone surgery Xenograft mix ed with Arginylglycylaspartic acid (RGD) and implant placement.

Both groups were followed up for 1 and 3 months after loading.

Enrollment: 18 estimated patients

Sex: All

Ages: 18 to 30 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Adults (age 18-30) exhibiting initial insufficiently bone width.
2. Patients with good oral hygiene.
3. Patients must be free from systemic diseases that may influence the outcome of the therapy.
4. Patients with bony horizontal defects alone, Class III & IV.

Exclusion criteria

1. Heavy smokers.
2. Patient treated by immunosuppressive chemotherapy or radio therapy,
3. Allergy to any material or medication used in the study.
4. Pregnant females.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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18 participants in 2 patient groups

Control Group

Active Comparator group

Description:

Xenograft alone with split-crest technique by ultrasonic bone surgery and implant placement.

Treatment:

Drug: Xenograft

Procedure: Split crest technique

Study Group

Experimental group

Description:

Xenograft mixed with RGD with split-crest technique by ultrasonic bone surgery and implant placement.

Treatment:

Drug: RGD

Drug: Xenograft

Procedure: Split crest technique