Efficacy of Zinc in the Treatment of Pneumonia

Johns Hopkins Bloomberg School of Public Health

Status: Completed

Conditions: Pneumonia

Treatments: Drug: Zinc

Study type: Interventional

Funder types: Other

Identifiers

NCT00198666

H.22.03.01.06.A2

Details and patient eligibility

About

This study is designed to evaluate the efficacy of zinc supplementation in the treatment of children under the age of two years who have been hospitalized with severe pneumonia.

Full description

This study was a randomized, double-blind, placebo-controlled clinical trial conducted between September 2003 and August 2004 at the Christian Medical College (CMC) Hospital in Vellore, India. CMC Hospital is a large teaching hospital and medical center that is accessed directly by the population of Vellore and adjoining districts and by referrals from local medical practitioners.

Enrollment: 299 patients

Sex: All

Ages: Under 23 months old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children under two years old hospitalized with Pneumonia

Exclusion criteria

• healthy children

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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299 participants in 2 patient groups

Treatment

Experimental group

Description:

Children with severe pneumonia were randomly assigned to receive supplementation with elemental zinc.

Treatment:

Drug: Zinc

Control

No Intervention group

Description:

Children with severe pneumonia were randomly assigned to receive supplementation with placebo tablets.