Efficacy Study of a Low Volume of Water Intake and Mosapride for Endoscopy in Patients With Subtotal Gastrectomy (SMW)

Inje University

Status and phase: Completed; Phase 3

Conditions: Foreign Body Left During Endoscopic Examination

Treatments: Drug: Mosapride

Study type: Interventional

Funder types: Other

Identifiers

NCT01284764

HGI-2011-01

Details and patient eligibility

About

A low volume of water intake and mosapride will effectively reduce food residue in remnant stomach for patients who had undergone subtotal gastrectomy due to gastric cancer.

Full description

We evaluate that a 500mL of water intake and mosapride will effectively reduce food residue in remnant stomach for patients who had undergone subtotal gastrectomy due to gastric cancer. We plan to compare this method with routine midnight fasting method for endoscopy in patients with subtotal gastrectomy.

Enrollment: 144 estimated patients

Sex: All

Ages: 18 to 80 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Outpatients who had subtotal gastrectomy for gastric cancer

Exclusion criteria

• Pregnancy
• Lactation
• History of anastomotic stricture
• Recurrent advanced gastric cancer
• Poor general condition( > 2 ECOG)
• Other disseminated malignancy
• Significant renal failure or congestive heart failure (CHF)
• Liver failure

Trial design

Primary purpose: Diagnostic

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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144 participants in 2 patient groups

midnight fasting

No Intervention group

Description:

The patients in this group will have midnight fasting the day before endoscopic examination

Mosapride, low volume of water

Active Comparator group

Description:

The patients in this group will take mosapride and a 500mL water at evening of the day before endoscopic examination.

Treatment:

Drug: Mosapride