Efficacy Study of Clinical Nutrition to Treat Lung Neoplasms And Breast Carcinoma

Chinese PLA General Hospital (301 Hospital)

Status: Completed

Conditions: Lung Neoplasms; Breast Neoplasms

Treatments: Drug: Maitake mushroom extract compound; Drug: Ginseng compound; Drug: GLSE compound

Study type: Interventional

Funder types: Other

Identifiers

NCT02603016

PLAGHS201503601

Details and patient eligibility

About

This study evaluates the efficacy of clinical nutrition to treat lung neoplasms and breast carcinoma.We estimate there will be 480 patients accepted.120 patients will receive GLSE compound,120 patients will recrive Maitake mushroom extract compound,120 patients will recrive Rinseng compound,and 120 patients will be as blank countrol group.Efficacy Study of Clinical Nutrition to Treat Lung Neoplasms And Breast Carcinoma

Full description

GLSE compound、Maitake mushroom extract compound and Rinseng compound have different mechanism on enhancing immunity.This clinicaltrial compare them the immune effect in the progress of treating lung neoplasms and breast carcinoma.Within the 42 days,we will abide by the plan to evaluate the immunity enhancement by monitoring mmune effector molecules.

Enrollment: 480 patients

Sex: All

Ages: 18 to 70 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• lung cancer and breast cancer patients confirmed by surgery pathology;
• ECOG physical stamina score of 0~3 points;
• Expected lifetime > 3 months;
• Need to receive radiation and chemotherapy;
• Heart, liver and kidney function and blood picture is normal,WBC≥4×109/L, neutrophil count≥ 2 x 109 / L,platelet count≥100×109/L, hemoglobin≥100 g/L;
• To follow-up, good adherence

Exclusion criteria

• Allergic to text drug;
• Pregnancy or lactation women;
• Suffering from mental illness of not easy to control,
• Have serious mental or cognitive dysfunction;
• Can not comply with the experimental scheme or can't cooperate with the follow-up;
• The patients who are unfavorable to the subject.

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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480 participants in 4 patient groups

GLSE compound group

Experimental group

Description:

GLSE compound 2g each time by mouth,twice a day for 42 days.

Treatment:

Drug: GLSE compound

Maitake mushroom extract compound group

Experimental group

Description:

Maitake mushroom extract compound 2 tables each time by mouth,twice a day for 42 days.

Treatment:

Drug: Maitake mushroom extract compound

Ginseng compound group

Experimental group

Description:

Ginseng compound 2 tables each time by mouth,twice a day for 42 days.

Treatment:

Drug: Ginseng compound

blank control group

No Intervention group

Description:

Take nothing.