Efficiency and Safety of Pleural Biopsy Methods in the Diagnosis of Pleural Diseases

Eskisehir Osmangazi University

Status: Completed

Conditions: Medical Thoracoscopy; Diagnosis of Pleural Diseases

Treatments: Diagnostic Test: CT-guided Abrams needle biopsy, US-guided cutting needle, medical thoracoscopy

Study type: Interventional

Funder types: Other

Identifiers

NCT03153501

PR-11-01-31-21

Details and patient eligibility

About

Image-guided pleural biopsies, both ultrasound (US) or computed tomography (CT) guided, and medical thoracoscopy are important in the diagnosis of pleural disease. However, no consensus exists regarding which biopsy methods are appropriate for specific procedures.

In this prospective study, the investigators aimed to compare CT-scan guided pleural biopsy using an Abrams' needle (CT-ANPB) with US-assisted pleural biopsy using a cutting needle (US-CNPB)and medical thoracoscopy with respect to both diagnostic yield and safety.

Full description

The primary end point of this study was the determination of the sensitivity and the complication rates of the invasive methods, Abrams needle pleural biopsy, tru-cut needle pleural biopsy, medical thoracoscopy with respect to the diagnosis of pleural disease.

Enrollment: 164 patients

Sex: All

Ages: 18 to 85 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients with pleural diseases

Exclusion criteria

• Patients with other lung diseases

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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164 participants in 1 patient group

Diagnostic arm

Other group

Description:

Patients with pleural diseases; malignant pleural diseases, tuberculous pleurisy, and other exudate required CT-guided Abrams needle biopsy, US-guided cutting needle biopsy, and medical thoracoscopy.

Treatment:

Diagnostic Test: CT-guided Abrams needle biopsy, US-guided cutting needle, medical thoracoscopy