Efficiency of the Quadratus Lumborum Block for Post-operative Analgesia in Abdominoplasty Surgery (QLB)

Centre Hospitalier Universitaire, Amiens

Status: Enrolling

Conditions: Quadratus Lumborum Block; Analgesia; Locoregional Anesthesia; Abdominoplasty

Treatments: Other: Intravenous anesthesia without QLB; Other: QLB anesthesia

Study type: Interventional

Funder types: Other

Identifiers

NCT04670224

PI2020_843_0094

Details and patient eligibility

About

Abdominoplasty is a common surgical procedure in plastic surgery which causes postoperative pain and may delay patients' recovery. Surgery is potentially associated with a number of postoperative complications, whether cardiovascular, respiratory, infectious, thromboembolic, or digestive ... Although they do not inevitably lead to a life-threatening prognosis, in many cases these complications delay post-operative recovery. Defined in the 1990s by Professor Henry Kehlet's Danish team, rapid rehabilitation after planned surgery is an approach to overall patient care that aims to rapidly restore previous physical and mental capacities and thus significantly reduce mortality and morbidity. Pain management is at the heart of this program and local anesthesia techniques are at the heart of early rehabilitation programs.

Described for just over a decade, Quadratus Lumborum Block (QLB) have shown their effectiveness for analgesia in abdominal, or orthopedic, or obstetrical surgery. Considering the anatomical territory concerned, this locoregional anesthesia technique seems to be very interesting in abdominoplasty to allow early rehabilitation of the patient.

Enrollment: 286 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult patients admitted for programmed dermo-lipectomy surgery with or without associated liposuction.

Exclusion criteria

• Pregnant woman
• Patient under 18 years of age
• Subject under guardianship or curators
• Patient allergic to local anesthetics
• Infection at the puncture sites
• Patient on morphine analgesic over the long term
• Patient on antidepressants for neuropathic pain.

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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286 participants in 2 patient groups

QLB technique

Experimental group

Treatment:

Other: QLB anesthesia

Intravenous anesthesia without QLB

Active Comparator group

Treatment:

Other: Intravenous anesthesia without QLB