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Efficient Postoperative Pain Management With Multimodal IV

B

Benha University

Status

Completed

Conditions

Post Operative Pain

Treatments

Drug: Multimodal IV analgesia
Drug: epidural analgesia

Study type

Interventional

Funder types

Other

Identifiers

NCT06661746
Rc 1-7-2024

Details and patient eligibility

About

Postoperative pain remains a prevalent concern despite ongoing improvements in surgical methods and pain management strategies. Opioids, while commonly prescribed, frequently lead to undesirable side effects. Epidural analgesia, though a viable option, carries its risks and complications. Recent research indicates that combining intravenous lidocaine and ketamine can significantly alleviate postoperative pain and decrease the reliance on opioids within the initial 24 hours following surgery. This approach offers a promising alternative with minimal additional adverse effects, suggesting a potential shift in pain management practices.

Enrollment

100 patients

Sex

All

Ages

35 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients were assigned for surgical intervention;
  • Patients of ASA grade I-III;
  • Patients were free of exclusion criteria;

Exclusion criteria

  • Patients who are not in ASA grade I-III;
  • Patients who had uncontrolled hypertension and/or diabetes mellitus;
  • Patients who had uncompensated cardiac, renal, or hepatic diseases;
  • Patients with coagulopathy, spinal deformity, allergy, or contraindication for the used drugs;
  • Patients who refused to sign the informed consent were excluded from the study.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

Single Blind

100 participants in 2 patient groups

Multimodal Group
Active Comparator group
Treatment:
Drug: Multimodal IV analgesia
Epidural Group
Active Comparator group
Treatment:
Drug: epidural analgesia

Trial contacts and locations

1

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Central trial contact

Eman El Afifi, MD

Data sourced from clinicaltrials.gov

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