EGD-assisted Bowel Preparation for Colonoscopy

Rockford Gastroenterology Associates

Status: Completed

Conditions: Esophagoscopy Techniques; Colonoscopy

Treatments: Procedure: EGD-assisted administration of colonoscopy prep; Procedure: Control Group received standard prep by oral administration

Study type: Interventional

Funder types: Other

Identifiers

NCT01563744

EGD-assisted 2012

Details and patient eligibility

About

Adequate bowel preparation is of critical importance for colonoscopy. Particularly among hospitalized patients, inadequate bowel preparation for colonoscopy may arise due to patient intolerance to prescribed laxative regimen, elderly population, and co-existing conditions that impair the ability to ingest a large-volume laxative regimen. Improvements in bowel preparation for colonoscopy in hospitalized patients would likely improve patient care and reduce hospital costs. The purpose of this study is to determine if administering a portion of the bowel purgative via EGD could improve colonoscopy preparation in hospitalized patients.

Full description

In this randomized controlled trial in hospitalized patients, patients in whom colonoscopy was anticipated the day following EGD were consented and randomized to either standard prep by mouth (split-dose PEG) or intervention group (instillation of the first 2 liters of Nulytely solution through the channel of the endoscope into the duodenal bulb, then continue standard prep). Data is collected on quality of prep and patient satisfaction in both groups.

Enrollment: 82 patients

Sex: All

Volunteers: No Healthy Volunteers

Inclusion criteria

• hospitalized patients
• having EGD and expected to have colonoscopy the following day
• written informed consent

Exclusion criteria

• unable to tolerate EGD-assisted prep administration

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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82 participants in 2 patient groups

EGD-assisted colonoscopy prep

Experimental group

Description:

2 liters of polyethylene glycol instilled through the channel of the endoscope during EGD when colonoscopy expected the following day. Patients follow a clear liquid diet, then ingest an addition 1 liter polyethylene glycol 4 hours prior to colonoscopy. Patients are also given a tap water enema 1 hour prior to colonoscopy.

Treatment:

Procedure: EGD-assisted administration of colonoscopy prep

Standard Colonoscopy Prep

Active Comparator group

Description:

Split-dose polyethylene glycol (2 liters pm prior to colonoscopy, 1 liter 4 hours prior to colonoscopy)), clear liquid diet, metoclopramide 10 mg IV 30 minutes prior to procedure, tap water enema 1 hr prior to colonoscopy

Treatment:

Procedure: Control Group received standard prep by oral administration