Ejaculatory-Sparing HoLEP vs Standard HoLEP

Northwestern University

Status: Enrolling

Conditions: Enlarged Prostate With Lower Urinary Tract Symptoms; Enlarged Prostate (BPH)

Treatments: Other: Ejaculatory-sparing (ES-sparing) HoLEP

Study type: Interventional

Funder types: Other

Identifiers

NCT07631286

STU00225807

Details and patient eligibility

About

The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.

Full description

The primary aim of this study is to assess the efficacy of ejaculatory-sparing HoLEP (ES-HoLEP) in preserving ejaculation while also maintaining good urinary outcomes.

Enrollment: 48 estimated patients

Sex: Male

Ages: 18 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

- Patients who are sexually active with antegrade ejaculation who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms.

Exclusion criteria

• Patients with pre-existing retrograde ejaculation
• Patients who are not sexually active
• Patients with indwelling urinary catheter prior to surgery, neurological disease, or history of prior prostatic/urethral surgery that may impact ejaculation
• Patients who lack decisional capacity
• Patients unable to read/speak English

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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48 participants in 2 patient groups

Standard HoLEP

No Intervention group

Description:

HoLEP procedure performed using standard care technique.

ES-HoLEP

Active Comparator group

Description:

HoLEP procedure performed using ejaculatory-sparing HoLEP technique.

Treatment:

Other: Ejaculatory-sparing (ES-sparing) HoLEP