Ejaculatory Sparing Transurethral Incision Of The Prostate (ES-TUIP) Versus Conventional TUIP

Mansoura University

Status: Unknown

Conditions: Ejaculatory Dysfunction; Prostate Hyperplasia; Transurethral Incision Of The Prostate

Treatments: Procedure: Ejaculatory sparing TUIP; Procedure: Conventional TUIP

Study type: Interventional

Funder types: Other

Identifiers

NCT03176017

HoLES-TUIP

Details and patient eligibility

About

In this study, Investigators planned to compare ejaculatory sparing and non-ejaculatory sparing (conventional) TUIP using both subjective and objective assessment tools for the degree of deobstruction.

Furthermore, the impact of both techniques on ejaculation and its secondary effect on orgasm perception and different domains of sexual function will be thoroughly assessed.

Enrollment: 40 estimated patients

Sex: Male

Ages: 40+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• American society of anesthesiologists (ASA) score ≤3.
• TRUS estimated prostate weight ≤ 35 grams.
• Sexually interested and having continuous relationship with the same partner (interested).
• Bladder outlet obstruction index (BOOI ) ≥ 20 as per pressure flow study

Exclusion criteria

• Preoperative sexual or ejaculatory disturbances or pelvic pain syndrome
• Neurological disorders that can affect potency and ejaculation e.g. long standing uncontrolled diabetes mellitus (DM) type 2 (> 10 years), DM type 1, cerebral stroke, Parkinsonism
• Urodynamic changes consistent with urethropathy or detrusor hypocontractility
• Previous pelvic surgeries or radiotherapy

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Single Blind

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40 participants in 2 patient groups, including a placebo group

Ejaculatory sparing TUIP

Active Comparator group

Description:

Ejaculatory sparing TUIP

Treatment:

Procedure: Ejaculatory sparing TUIP

Conventional TUIP

Placebo Comparator group

Description:

regular non ejaculatory sparing TUIP

Treatment:

Procedure: Conventional TUIP