Elastographic Imaging of Renal Transplants (Elastorenal)

The University of Texas System (UT)

Status and phase: Terminated; Phase 1

Conditions: Renal Transplant

Treatments: Other: Elastographic imaging

Study type: Interventional

Funder types: Other

Identifiers

NCT00935727

HSC-MS-06-0255

Details and patient eligibility

About

The study was developed to acquire images of normal, then abnormal, then unknown diagnosis for transplanted kidneys in order to determine whether the elastography imaging modality, a type of ultrasound imaging, can provide data useful for diagnosis of renal transplant abnormalities.

The specific aims of this study are:

1. To define normal elastography imaging by correlation with clinical findings.
2. To define specific abnormal elastography images by correlation with clinical findings.
3. To determine whether elastography could be useful in early diagnosis of abnormalities of renal transplants, especially in early rejection.

Full description

The study is collecting standard ultrasound and elastographic images of transplanted kidneys in order to perfect the imaging technique to get the best pictures, and to evaluate these images for characteristics that may be of diagnostic value.

Enrollment: 10 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Adult (over 18) male or female renal transplant patient
• normally functioning
• or being evaluated for a possible problem

Exclusion criteria

• unwilling or unable to give informed consent

Trial design

Primary purpose: Diagnostic

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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10 participants in 3 patient groups

1

Other group

Description:

normally functioning transplanted kidneys

Treatment:

Other: Elastographic imaging

2

Other group

Description:

transplanted kidney undergoing known rejection or other known abnormality

Treatment:

Other: Elastographic imaging

3

Other group

Description:

transplanted kidney with unknown diagnosis

Treatment:

Other: Elastographic imaging