Elastography in Patients With Idiopathic Inflammatory Myopathies

Benha University

Status: Unknown

Conditions: Idiopathic Inflammatory Myopathies

Treatments: Diagnostic Test: strain elastography

Study type: Observational

Funder types: Other

Identifiers

NCT03897803

BenhaU2022019

Details and patient eligibility

About

The aim of our study was to assess the performance of compression-strain US elastography in patients with idiopathic inflammatory myopathies over time and to study these findings with clinical and functional parameters as well as biochemical and electromyographic tests.

Full description

This study will be carried out on four groups:

Group (I): twenty children diagnosed to have idiopathic inflammatory myopathies(IIM)

• Group (II): twenty adults diagnosed to have IIM
• Group (III):20 healthy children matching age and sex as first control group to children with IIM .
• Group (VI):20 healthy adults matching age and sex as second control group to adults with IIM.

All patients will be evaluated at baseline at & 4-months follow up using Semi-Quantitative strain elastography

Enrollment: 80 estimated patients

Sex: All

Ages: 2+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• to fulfill criteria of diagnosis of childhood and adult idiopathic inflammatory myopathies

Exclusion criteria

• Patients with age less than 2 years were excluded from the study due to inability to perform manual muscle testing and functional scales.
• The presence of a associated illness that may result in nerve or muscle affection

Trial design

80 participants in 4 patient groups

Group (I):juvenile dermatomyositis (JDM)

Description:

Group (I): twenty children diagnosed to have juvenile dermatomyositis (JDM) Who will be evaluated using using strain elastography to assess muscle stiffness at baseline and after 4 months. .

Treatment:

Diagnostic Test: strain elastography

Group (II):idiopathic inflammatory myopathies(IIM)

Description:

Group (II): twenty adults diagnosed to have idiopathic inflammatory myopathies(IIM) Who will be evaluated using using strain elastography to assess muscle stiffness at baseline and after 4 months. * •

Treatment:

Diagnostic Test: strain elastography

Group (III): juvenile control group

Description:

20 healthy children matching age and sex as first control group to children with JDM .Who will be evaluated at baseline using using strain elastography to assess muscle stiffness . .

Treatment:

Diagnostic Test: strain elastography

Group (VI):adult control group

Description:

20 healthy adults matching age and sex as second control group to adults with IIM. Who will be evaluated at baseline using using strain elastography to assess muscle stiffness .

Treatment:

Diagnostic Test: strain elastography