Elderberries and Obesity

Washington State University

Status

Completed

Conditions

Fuel Management

Treatments

Other: Placebo beverage

Other: Elderberry juice

Study type

Interventional

Funder types

Other

Identifiers

NCT05723497

18682

Details and patient eligibility

About

Previous studies in humans indicate that anthocyanin-rich berries can positively alter fat oxidation and insulin sensitivity. This study will determine if this is also true with elderberries, which are a more concentrated source of anthocyanins compared to other commonly consumed berries.

Enrollment

10 patients

Sex

All

Ages

22 to 75 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

Women and Men between 22 and 75 years of age with a body mass index of 25 kg/m2 or above.

Exclusion criteria

Are not fully vaccinated against COVID-19 (at least 2-weeks out from final dose at time of staff meeting)
Have a body mass index less than 25 kg/m2
Are younger than 22 years of age, or older than 75 years of age
Pregnant, lactating, or intending to become pregnant during the study period, or have given birth in the past year
Known allergy or intolerance to elderberries
History of bariatric surgery or nutrient malabsorption disease (such as celiac disease) or other metabolic disorders requiring a special diet that is not in accord with the diet behavior requested for this study
Adherence to restrictive (vegetarian or vegan) or extreme (fad [ex. Ketogenic or Atkins] or quick weight loss/gain) diet patterns and unwillingness to consume a conventional, omnivorous diet and maintain body weight
Habitual use of tobacco or marijuana (including vaping) products in the last 6 months
Diagnosis or treatment of cancer in the past 3 years
Crohn's disease or diverticulitis
Suspected or known strictures, fistulas or physiological/mechanical GI obstruction
Use of certain medications (prescription or over-the-counter) that may interfere with the study objectives, including blood thinning medications
Type 2 diabetes requiring the use of medication
Fasting blood glucose > 125 mg/dL
Unable or unwilling to give informed consent or communicate with study staff
Self-report of alcohol or substance abuse within the past 12 months and/or current treatment for these problems (long-term participation in Alcoholics Anonymous is not an exclusion)
Other medical, psychiatric, or behavioral factors that in the judgment of the Principal Investigator may interfere with study participation or the ability to follow the intervention protocol