Electrical Impedance Imaging of Patients on Mechanical Ventilation

Colorado State University (CSU)

Status: Completed

Conditions: Pneumothorax; Pleural Effusion; Hyperinflation; Acute Respiratory Distress Syndrome; Emphysema; Atelectasis; Pulmonary Contusion; Pulmonary Edema

Treatments: Device: CT Scan; Device: Mechanical Ventilation

Study type: Observational

Funder types: Other; NIH

Identifiers

NCT02232841

1R21EB016869-01A1 (U.S. NIH Grant/Contract)

13-4656H

Details and patient eligibility

About

The goal of this study is to evaluate the sensitivity and specificity of Electrical Impedance Tomography (EIT) as a bedside diagnostic tool for lung pathologies in patients who are mechanically ventilated. In electrical impedance tomography low amplitude, low frequency current is applied on electrodes, and the resulting voltage is measured and used to computed the electrical properties of the interior of the chest as they change in time. The computed properties are used to form an image, which can then be used for monitoring and diagnosis.

Full description

The goal of this study is to characterize the ability of the electrical impedance tomography system (hardware and software) to distinguish between lung pathologies by assessing the sensitivity and specificity as well as the overall agreement with the CT scan in terms of spatial resolution. The study will test, as well as refine, the mathematical algorithms needed to create meaningful outputs on adult patients receiving mechanical ventilation and who also have received or will be receiving a CT scan as part of their standard of care.

Enrollment: 2 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients admitted to the ICU at Medical Center of the Rockies and on mechanical ventilation
• Age greater than or equal to 18
• Computed Tomography of the chest during normal course of hospital admission

Exclusion criteria

• Age <18
• Any skin disorder that would prevent placement of the electrodes on the chest wall
• Hemodynamic instability prohibiting patient from being moved to place the device

Trial design

2 participants in 1 patient group

Mechanical ventilation

Description:

Hospitalized adult patients with lung injury receiving mechanical ventilation and who also have received or will receive a CT scan as part of their standard care

Treatment:

Device: CT Scan

Device: Mechanical Ventilation