Electrical Impedance Tomography of Lung in Child and Young Age (EIT-Lunge)

RWTH Aachen University

Status: Completed

Conditions: Obstructive Lung Diseases

Treatments: Procedure: probands; Procedure: patients

Study type: Observational

Funder types: Other

Identifiers

NCT02290535

12-076

CIV-14-03-011942 (Other Identifier)

Details and patient eligibility

About

The investigator will determine a compliance of two diagnostic techniques (EIT and Body plethysmography) in collective of children and teenagers with obstructive lung disease and a matched control group.

Full description

The aim of the present study is verification of the correlation between EIT-derived data and following extracted parameters of the pulmonary function:

• forced expiratory volume in 1 second (FEV 1)
• forced vital capacity (FVC)
• relative forced expiratory volume in 1 second (FEV1/FVC)
• maximal expiratory flow (MEF 25)
• total lung capacity (TLC)
• resistance (Raw).

These findings could bring out new prospective opportunity for pulmonary function tests without cooperation.

Furthermore, the study aims to clarify whether EIT technique can be used for regional pulmonary function testing.

In addition, dynamic lung function parameter and static radiological techniques will be correlated with EIT.

Enrollment: 192 patients

Sex: All

Ages: 5 to 18 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Patients: children and teenagers with obstructive pulmonary disease (asthma, cystic fibrosis, immotile-cilia-syndrome, obstructive brochitis, obstructive pneumonia).
• Probands: Children and Teenager of 5-18 years without known obstructive pulmonary diseases

Exclusion criteria

• active implants (ICD, CRT)
• metal in chest
• artificial heart valve
• children < 5 years
• pregnant and lactating females
• Persons, who are in relationship of dependence to the investigator / sponsor
• Persons, who are not able to understand and follow the instructions of the study personnel.
• Lack of signed informed consent (by legal guardian /proband)

Trial design

192 participants in 2 patient groups

Patients

Description:

Children and Teenager of 5-18 years with obstructive pulmonary disease (asthma, cystic fibrosis, immotile-cilia-syndrome, obstructive bronchitis, obstructive pneumonia).

Treatment:

Procedure: patients

Probands

Description:

Children and Teenager of 5-18 years without known obstructive pulmonary diseases

Treatment:

Procedure: probands