Electrical Muscle Stimulation in the Development of Acquired Weakness in Patients With Severe Sepsis and Septic Shock

University of Chile

Status: Completed

Conditions: Polyneuropathies; Muscle Weakness; Septic Shock

Treatments: Device: electrical muscle stimulation; Procedure: conventional physical therapy

Study type: Interventional

Funder types: Other

Identifiers

NCT03765489

OAIC 847/16

Details and patient eligibility

About

The aim of this study is to compare the effect of EMS and conventional physical therapy on strength and muscle mass and development in adult patients with severe sepsis and septic shock.

Full description

Septic patients are at high risk of developing intensive care unit acquired weakness (ICUAW). Electrical muscle stimulation (EMS) has become an alternative exercise for critical and non-cooperative patients.

Enrollment: 23 patients

Sex: All

Ages: 18+ years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Subjects admitted to the ICU of the HCUCH in the period between November 2016 to August 2017 and January to June 2018
• Diagnosis of severe sepsis or septic shock
• More than 48 hours in VMI
• With sedation and / or neuromuscular blockade
• Autovalent prior to admission to the ICU

Exclusion criteria

• Subjects from other hospitals / clinics or units of the hospital
• Multiple trauma
• Previous neuromuscular pathology
• Pacemaker users
• Pregnant women
• BMI> 35
• Epilepsy
• Those who have refused to sign informed consent

Trial design

Primary purpose: Prevention

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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23 participants in 2 patient groups

electrical muscle stimulation

Experimental group

Description:

conventional physical therapy according to the adaptation of the "Start to move" protocol of Gosselink et al. plus electrical muscle stimulation: The parameters used in biceps were: 35 Hz, 250 μs and in quadriceps were: 50 Hz, 400 μs. In both, biphasic wave was used, 45 minutes of total work, 5 seconds of contraction and 10 seconds of relaxation and the intensity was adjusted to present a visible contraction

Treatment:

Device: electrical muscle stimulation

Procedure: conventional physical therapy

conventional physical therapy

Active Comparator group

Description:

conventional physical therapy according to the adaptation of the "Start to move" protocol of Gosselink et al

Treatment:

Procedure: conventional physical therapy