Electrical Stimulation to Strengthen Muscles in the Lower Legs in Patients Requiring Prolonged Mechanical Ventilation

RML Specialty Hospital

Status: Completed

Conditions: Muscle Weakness

Treatments: Device: Neuromuscular electrical stimulation; Device: sham stimulation

Study type: Interventional

Funder types: Other

Identifiers

NCT01825135

AXJ012

Details and patient eligibility

About

The primary aim of this proposal is to test the effectiveness of NMES in improving functional status and muscle function in patients requirng prolonged mechanical ventilation

Enrollment: 57 patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• duration of mechanical ventilation for 14 days or more
• sufficiently awake
• able to speak and comprehend English

Exclusion criteria

• known primary neuromuscular disease
• lower extremities paresis or amputee
• patients with left-ventricular assist device (LVAD)
• cardiopulmonary instability

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Double Blind

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57 participants in 2 patient groups

Neuromuscular electrical stimulation

Experimental group

Description:

Neuromuscular electrical stimulation (NMES) will be applied to the quadriceps muscles for 30 minutes

Treatment:

Device: Neuromuscular electrical stimulation

Sham stimulation

Sham Comparator group

Description:

Sham stimulation will be applied to the quadriceps for 30 minutes

Treatment:

Device: sham stimulation