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Electroacupuncture Preconditioning on Geriatric Noncardiac Surgery

A

Air Force Military Medical University of People's Liberation Army

Status

Unknown

Conditions

Coronary Heart Disease

Treatments

Device: EA preconditioning
Device: sham EA preconditioning

Study type

Interventional

Funder types

Other

Identifiers

NCT01507805
csyxijing

Details and patient eligibility

About

The purpose of this study is to observe whether the electroacupuncture (EA) preconditioning for five days before operation can improve the outcomes of patients with coronary heart disease undergoing geriatric non-cardiac surgery.

Full description

BACKGROUND:

With the development of surgical techniques, more and more people with coronary heart disease underwent non-cardiac surgery, which include abdominal, urologic, orthopedic surgeries. Due to the vulnerable heart function, geriatric patients suffer high incidence of cardiovascular events during the peri-operative period. Some studies found that EA preconditioning have a protective effect for the patients underwent Cardiac surgery. But non one addresses the effects of EA preconditioning on the outcomes of the patients with coronary heart disease who undergo non-cardiac surgery.

DESIGNING:

The patients with coronary heart disease who will receive abdominal surgery will be randomly assigned into EA preconditioning group and control group. The patients in EA preconditioning group was treated at bilateral Neiguan (PC 6),Lieque (LU 7) and Yunmen (LU 2) with electrical stimulation (5-30 Hz,2.34-6.24 mA,30 min) for 5 consecutive days before surgery.Before operation and before surgery, after surgery, 24h, 72h post surgery, all patients will be subjected to test the serum level of c-reactive protein and Troponin I. The EEG and heart ultrasonic exam will be used to evaluate the condition and function of heart before and after surgery.

Enrollment

300 estimated patients

Sex

All

Ages

65+ years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • elective abdominal surgery with coronary heart disease

Exclusion criteria

  • serious bradycardiac arrythmia

Trial design

Primary purpose

Prevention

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

300 participants in 2 patient groups

EA preconditioning
Experimental group
Description:
electroacupuncture five days pre-operation
Treatment:
Device: EA preconditioning
Sham EA preconditioning
Sham Comparator group
Description:
Patients treated with sham EA preconditioning Intervention
Treatment:
Device: sham EA preconditioning

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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