Electrocardiographic Changes Among Epileptic and Non Epileptic Seizures in Children at Sohag University Hospital

Sohag University

Status: Not yet enrolling

Conditions: Seizures

Treatments: Device: ECG

Study type: Observational

Funder types: Other

Identifiers

NCT06045676

Soh-Med-23-09-06MS

Details and patient eligibility

About

Epilepsy is a chronic disease triggered by increased impulsiveness of nerve cells in the brain and may require a lifelong treatment. Epilepsy is confirmed by two or more unprovoked seizures in more than 24 hours. Febrile Convulsion is another type of seizure occurring due to fever over 38 °C without a history of convulsion, CNS infection, electrolyte imbalance, metabolic disorder, intoxication, and trauma. Unlike epileptic seizures, there are non-epileptic seizures such as Breath Holding Spells that affect children's behaviors and often look like epileptic seizures.

QT parameters elongation show the danger of dysrhythmia and unexpected sicknesses such as cardiomyopathy, mitral valve prolapse, ischemic coronary illness, and kidney disorders.

Many investigators have reported changes in QT parameters in various diseases such as diabetes mellitus, celiac disease, thalassemia , epilepsy ,Breath holding spells and febrile seizure.

Enrollment: 160 estimated patients

Sex: All

Ages: 1 to 12 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• children with drug resistant epilepsy.
• febrile seizures.
• age of 1 year to 12 years.

Exclusion criteria

• age below 1 year and above 12 years
• children with convulsion secondary cns infection , encephalitis, encephalopathy , toxic and metabolic problem

Trial design

160 participants in 5 patient groups

Drug Resistant Epilepsy

Description:

Seizures Not Respond to two lines of Anti epileptic Medications

Treatment:

Device: ECG

Drug Responsive Epilepsy

Description:

Seizures Respond to one or two lines of Anti epileptic Medications

Treatment:

Device: ECG

Febrile Seizures

Description:

type of seizure occurring due to fever over 38 °C without a history of convulsion

Treatment:

Device: ECG

Breath Holding Spells

Description:

children's behaviors look like epileptic seizures due to crying up to a minute followed by losing consciousness

Treatment:

Device: ECG

Control

Description:

Healthy Children free from any convulsion

Treatment:

Device: ECG