Electrochemotherapy in Musculoskeletal Tumors

Costantino Errani

Status: Active, not recruiting

Conditions: Bone Tumors

Study type: Observational

Funder types: Other

Identifiers

NCT07323017

ELECTRO

Details and patient eligibility

About

The study involves the enrollment of patients over 2 years of age with a diagnosis of musculoskeletal tumors and an indication for electrochemotherapy, treated at the Rizzoli Orthopaedic Institute in Bologna and followed during outpatient follow-up. Data will be collected from medical records, outpatient reports, and imaging studies including CT, X-ray, MRI, and/or PET.

For the retrospective part of the study, patients treated at the Rizzoli Orthopaedic Institute from 01/01/2024 to the date of approval of this study will be included. For the prospective part, patients meeting the inclusion criteria and treated from the study start date until 31/12/2030 will be enrolled.

Enrollment: 60 estimated patients

Sex: All

Ages: 2+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients of both sexes with a histological diagnosis of a primary musculoskeletal tumor, either benign or malignant, located outside the abdominal cavity (trunk and limbs)

• Indication for electrochemotherapy due to one of the following conditions:

  1. Clinical conditions contraindicating surgery
  2. Tumor not surgically resectable

• Patients treated with electrochemotherapy at the Rizzoli Orthopaedic Institute:

  1. From 01/01/2024 to the date of study approval for the retrospective phase
  2. From the date of study approval to 12/31/2030 for the prospective phase

• Retrospectively treated patients with a minimum follow-up of at least 3 months

• Age ≥ 2 years at the time of treatment

• Availability of clinical and instrumental data

Exclusion criteria

• Failure to meet at least one of the inclusion criteria