Electrocorticographic Monitoring of Brain Retraction Injury (EMBRI)

University College London (UCL)

Status: Enrolling

Conditions: Brain Ischemia; Brain Injury; Neurosurgery

Treatments: Other: ECOG Array

Study type: Interventional

Funder types: Other

Identifiers

NCT06409806

310742

Details and patient eligibility

About

A single centre IDEAL Stage 1 feasibility study using novel electrophysiological recording techniques in adult participants undergoing neurosurgery. This is a first in human study, building upon previous preclinical mice experiments.

Participants will undergo their planned neurosurgical procedure as normal. In addition to their standard treatment neurophysiological monitoring including an electrocorticography electrode placed on the brain deep to the retractor will be used to monitor for signs of brain retraction injury.

Enrollment: 6 estimated patients

Sex: All

Ages: 16+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Patients aged 16 or older undergoing intracranial surgery where it is anticipated fixed brain retraction will be used.

Exclusion criteria

• Patients without capacity to give consent at time of recruitment

Trial design

Primary purpose: Other

Allocation: N/A

Interventional model: Single Group Assignment

Masking: None (Open label)

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6 participants in 1 patient group

Intervention arm

Experimental group

Treatment:

Other: ECOG Array