Electroencephalography in the Management of Neuroelectric Stimulation in Patients With Severe Traumatic Brain Injuries

Shanghai Jiao Tong University

Status: Enrolling

Conditions: Brain Injuries

Study type: Observational

Funder types: Other

Identifiers

NCT06571032

LY2024-007

Details and patient eligibility

About

The goal of this observational retrospective study is to evaluate the electroencephalography (EEG)'s poficiency in the treatment of neuroelectric stimulation in patients with severe traumatic brain injuries (TBI).

The main questions it aims to answer are:

1. Whether EEG of patients with severe TBI will change after they receiving neuroelectrial stimulation? If yes, how does it change?
2. How can EEG be used to evaluate the condition of patients with severe TBI?

Enrollment: 50 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 7 days after severe traumatic brain injuries (GCS score 3-8);
• Over 18 years old, regardless of gender;
• The patient's legal representative is informed and voluntarily signs the consent form.

Exclusion criteria

• Unstable vital signs;
• History of mental disorders or neurodegenerative diseases;
• Uncontrolled epilepsy;
• Severe arrhythmias or patients with implanted cardiac pacemakers;
• Various conditions that interfere with scalp EEG collection;
• Pregnant women.

Trial design

50 participants in 2 patient groups

Consicousness improved group

Description:

After receiving neuroelectrial stimulation, the patients with severe TBI have the consciousness improvement (CRS-R score is higher than before).

Consicousness unimproved group

Description:

After receiving neuroelectrial stimulation, the patients with severe TBI have no consciousness improvement (CRS-R score remains the same as before).