Electrolytes in Chronic Kidney Disease Patients With Acute Coronary Syndrome

Sohag University

Status: Unknown

Conditions: Acute Coronary Syndrome

Treatments: Diagnostic Test: Serum Calcium

Study type: Observational

Funder types: Other

Identifiers

NCT05134220

Electrolytes

Details and patient eligibility

About

Study of serum calcium and phosphorus level in chronic kidney disease patients and its relation to occurrence of acute coronary syndrome in them.

Full description

Prospective study to :

1. find the relation between electrolytes disturbance and renal diseases
2. the effect of electrolyte abnormalities on atherosclerosis
3. prevalence of acute coronary syndrome in patients with chronic kidney disease

Enrollment: 100 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• 1-The CKD patients with or without dialysis who admitted to coronary care unit with chest pain consistent with ACS with any of following features :

  a- Electrocardiogram (ECG) changes:

• ST elevation.

• ST depression.

• T wave inversion.

• recent left bundle branch block.

  b- Troponin T elevation.

  2-The CKD patient with or without dialysis with no previous history of ACS.

Exclusion criteria

1. Patients who were diagnosed with primary hyperparathyroidism.

2. Acute Kidney injury (AKI) which is defined as any of the following:(KDIGO2012)

   • Increase in S.Cr by ≥ 0.3 mg/dl (≥ 26.5 μmol/l) within 48hours; or
   • Increase in S.Cr to ≥ 1.5 times baseline, which is known or presumed to have occurred within the prior 7 days;or
   • Urine volume <0.5 ml/kg/h for 6 hours

Trial design

100 participants in 2 patient groups

Chronic Kidney Disease (CKD) patients with acute coronary syndrome

Description:

The CKD patients with or without dialysis who admitted to coronary care unit with chest pain consistent with ACS with any of following features : 1. Electrocardiogram (ECG) changes: * ST elevation. * ST depression. * T wave inversion. * recent left bundle branch block. 2. Troponin elevation.

Treatment:

Diagnostic Test: Serum Calcium

Chronic Kidney Disease (CKD) patients without acute coronary syndrome

Description:

The CKD patient with or without dialysis with no previous history of ACS.

Treatment:

Diagnostic Test: Serum Calcium