Electromyographic (EMG) on the Anaesthesia Monitor

Tampere University Hospital

Status and phase: Completed; Phase 4

Conditions: Anaesthesia

Treatments: Drug: Rocuronium bromide

Study type: Interventional

Funder types: Other

Identifiers

NCT01142635

2008-008129-31 (EudraCT Number)

R08197M

Details and patient eligibility

About

Intubation may induce electromyographic (EMG) activity, causing depth of anaesthesia monitors to show misleadingly high values. The investigators want to investigate whether this EMG activity can be visually seen on the anaesthesia monitor.

Full description

Patients are anaesthetized with target controlled infusion of propofol. To facilitate intubation, the patients are randomized to receive rocuronium either 0,6 mg/kg or 1,2 mg/kg. BIS, Entropy and the biosignal collected with the Entropy strip are collected on a computer. The visible biosignal on the anaesthesia monitor is recorded with a video camera. BIS, Entropy, biosignal and video clip of the anaesthesia monitor will be analyzed in detail.

Enrollment: 30 estimated patients

Sex: Female

Ages: 18 to 65 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• females giving informed consent
• age range 18-65 years
• elective surgery: gynaecological
• general anaesthesia
• ASA classification 1 or 2

Exclusion criteria

• pregnancy
• body mass index > 30
• disease affecting CNS
• overuse of alcohol
• drug abuse
• unability to understand, read or use Finnish language

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind