Electronic Health Mindfulness-based Music Therapy Intervention for Patients Undergoing Allogeneic Stem Cell Transplantation

University of Miami

Status: Active, not recruiting

Conditions: Stem Cell Transplantation; Leukemia, Myeloid, Acute; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Lymphoma, Non-Hodgkin; Myelodysplastic Syndromes

Treatments: Behavioral: Mindfulness Meditation (MM); Behavioral: Mindfulness-based Music Therapy (MBMT)

Study type: Interventional

Funder types: Other; NIH

Identifiers

NCT05968963

1R61CA263335-01A1 (U.S. NIH Grant/Contract)

20230726

Details and patient eligibility

About

The goal of this study is to pilot test an Electronic Health Mindfulness-based Music Therapy Intervention (eMBMT) intervention to improve health-related quality of life (HRQoL) and reduce symptom burden of patients undergoing allogeneic stem cell transplantation (allo-SCT).

Enrollment: 60 estimated patients

Sex: All

Ages: 18+ years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• ≥ 18 years of age
• have a primary diagnosis of myelodysplastic syndrome (MDS), acute myeloid leukemia (AML), acute lymphoblastic leukemia (ALL), or non Hodgkin's Lymphoma (NHL)
• have a treatment plan for an allogeneic hematopoietic stem cell transplant
• Speak English or Spanish

Exclusion criteria

• history of severe psychiatric illness (e.g., psychosis, active suicidality, inpatient treatment in the past 12 months)
• severe cognitive impairment (per the short portable mental status questionnaire)
• hearing impairment
• active alcohol or substance dependence within the past six months
• participated in music therapy or mindfulness programs in the past six months

Trial design

Primary purpose: Supportive Care

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: None (Open label)

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60 participants in 2 patient groups

Mindfulness-based Music Therapy (MBMT)

Experimental group

Description:

Participants will be in the MBMT group for 5 months.

Treatment:

Behavioral: Mindfulness-based Music Therapy (MBMT)

Mindfulness Meditation (MM)

Experimental group

Description:

Participants will be in the MM group for 5 months.

Treatment:

Behavioral: Mindfulness Meditation (MM)