Electronic Health Record Strategies to Promote Diverse Participation in Research
Status
Completed
Conditions
Patient Participation
Treatments
Other: Traditional Letter
Other: Banner
Other: Direct to Patient Message
Other: Chatbot
Study type
Interventional
Funder types
Other
Other U.S. Federal agency
Identifiers
Details and patient eligibility
About
The purpose of this study is to determine the effectiveness of enhanced features in an online patient portal including banners, a chatbot, and direct to patient message and traditional mailed letters on increasing interest in research among online patient portal users.
Full description
The primary objective is to examine the effectiveness of enhanced online patient portal features including banners, a chatbot, and direct to patient message and traditional mailed letters on increasing interest in research among online patient portal users, as measured by the user's creation of a research profile.
The secondary objective is to examine the effectiveness of two enhanced online patient portal features including banners, a chatbot and direct-to-patient messages and traditional mailed letters on increasing participation in research among online patient portal users, as measured by the user joining a research study.
This study tests the hypothesis that at one year follow-up, various user engagement tools (e.g. messaging, banners) will increase the proportion of research profiles created by online patient portal users over profiles created by online patient portal users in the absence of those interventions.
Enrollment
726,199 patients
Sex
All
Ages
18+ years old
Volunteers
Accepts Healthy Volunteers
Inclusion criteria
- Has an account with the online patient portal
- Has logged into the online patient portal at least once in the past year
- Has not set up a research profile
Exclusion criteria
- Currently enrolled in a clinical trial
- Opted out of research
- Has received a direct to patient recruitment message within the past year
- On active cancer treatment
- Active member of the study team
Trial design
Primary purpose
Other
Allocation
Randomized
Interventional model
Factorial Assignment
Masking
Double Blind
726,199 participants in 16 patient groups
No Intervention
No Intervention group
Description:
\*No intervention.
Traditional Letter Only
Experimental group
Description:
\*A mailed letter will invite the patient to set up a research profile in their patient portal.
Treatment:
Other: Traditional Letter
Direct to Patient Message Only
Experimental group
Description:
\*An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research.
Treatment:
Other: Direct to Patient Message
Chatbot Only
Experimental group
Description:
\*A real-time, interactive chatbot on the patient portal will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests.
Treatment:
Other: Chatbot
Banner Only
Experimental group
Description:
\*Banner-type "advertisements" will appear during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Traditional Letter + Direct to Patient Message
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research.
Treatment:
Other: Direct to Patient Message
Other: Traditional Letter
Traditional Letter + Chatbot
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests.
Treatment:
Other: Chatbot
Other: Traditional Letter
Traditional Letter + Banner
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Other: Traditional Letter
Direct to Patient Message + Chatbot
Experimental group
Description:
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research; AND
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests.
Treatment:
Other: Direct to Patient Message
Other: Chatbot
Direct to Patient Message + Banner
Experimental group
Description:
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research AND
* Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Other: Direct to Patient Message
Chatbot + Banner
Experimental group
Description:
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about clinical trial opportunities and trials that match their interests; AND
* Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care will inform patients of research opportunities.
Treatment:
Other: Banner
Other: Chatbot
Traditional Letter + Direct to Patient Message + Chatbot
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research; AND
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests.
Treatment:
Other: Direct to Patient Message
Other: Chatbot
Other: Traditional Letter
Traditional Letter + Direct to Patient Message + Banner
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research; AND
* Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Other: Direct to Patient Message
Other: Traditional Letter
Traditional Letter + Chatbot + Banner
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests.
AND
\*Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Other: Chatbot
Other: Traditional Letter
Direct to Patient Message + Chatbot + Banner
Experimental group
Description:
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research; AND
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests; AND
* Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Other: Direct to Patient Message
Other: Chatbot
Traditional Letter + Direct to Patient Message + Chatbot + Banner
Experimental group
Description:
* A mailed letter will invite the patient to set up a research profile in their patient portal; AND
* An e-mail sent to the patient will inform the patient that there is a message pending in their patient portal regarding opportunities to participate in research; AND
* A real-time, interactive chatbot will encourage research participation and direct patients to learn more about research opportunities and trials that match their interests; AND
* Banner-type "advertisements" during routine viewing and use of of the patient's portal for their our medical/clinical care inform patients of research opportunities.
Treatment:
Other: Banner
Other: Direct to Patient Message
Other: Chatbot
Other: Traditional Letter
Trial contacts and locations
1
Loading...
Central trial contact
Helen Seow, PhD
Data sourced from clinicaltrials.gov
Clinical trials
Research sites
Resources
Legal
© Copyright 2026 Veeva Systems