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Electronic Nose and Fetal Chromosomal Disorders

R

Rambam Health Care Campus

Status

Unknown

Conditions

Detecting Abnormal Fetal Karyotype by the Electronic Nose

Treatments

Other: observational study done only in women candidate for amniocentesis

Study type

Observational

Funder types

Other

Identifiers

NCT02579213
0200-15-RMB

Details and patient eligibility

About

"electronic nose"- the tiny sensors, will smell and detect the changes in the sample of abnormal fetal karyotype, and fluid that will be confirmed by amniocentesis.

Full description

The biochemical engineering department had developed a device called "electronic nose" that can detect various diseases Including cancer and asthma on basis of evaporable substances. The device simulates the human nose ", which includes an array of tiny sensors connected to nanometric sizes electronic calculating unit.. Thanks to their small size, electrical, physical and chemical properties, the sensitive sensors smell and identified changes in composition of the materials that characterize various diseases including kidney disease and asthma.

The electronic nose was developed by Professor Haick from the Technion. The main concept of the device is testing and characterization a trace amounts of substances in the air with the help of nana-technology sensors the idea is revolutionary and would allow the diagnosis of different diseases, like cancer, by exhaling air into the device.

The test is simple and not complicated to perform ,the examiner inhale air into a bag which connected to the "electronic nose". The molecules of the patient's breath will be tied to sensors and transmit an electrical signal to computer chip.

After processing the data the "electronic nose "can distinguish between normal cells and pathological cells.

Hypothesis: the tiny sensors ("electronic nose") will smell and detect the changes in the sample of abnormal fetal karyotype, and fluid that will be confirmed by amniocentesis.

Enrollment

500 estimated patients

Sex

Female

Ages

16 to 45 years old

Volunteers

Accepts Healthy Volunteers

Inclusion criteria

  • Pregnant women candidates for amniocentesis
  • 17-33 gestational weeks

Exclusion criteria

  • women that refuse to participate in the research
  • women older than 45 or less than 16

Trial design

500 participants in 1 patient group

women candidates for amniocentesis
Description:
pregnant women candidates for amniocentesis between 17-33 gestational weeks
Treatment:
Other: observational study done only in women candidate for amniocentesis

Trial contacts and locations

0

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Data sourced from clinicaltrials.gov

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