Electronic Real-Time Heart Team Decision-making vs. Usual Care in Patients With Triple-Vessel Coronary Artery Disease and Diabetes Mellitus (EHEART-3VD)

National Center for Cardiovascular Diseases

Status

Not yet enrolling

Conditions

Coronary Artery Disease

Diabetes

Treatments

Other: Real-Time Heart Team Decision-making

Study type

Interventional

Funder types

Other

Identifiers

NCT07326514

2025-2850

Details and patient eligibility

About

This is a multi-center randomized controlled trial involving patients with 3-vessel coronary artery disease and diabetes mellitus. Enrolled patients will be dividing into real-time heart team decision-making group (intervention group) and usual care group (control group). The intervention group will conduct a real-time online multidisciplinary heart team discussion and decision-making during coronary angiography. The control group will conduct an usual care decision-making.

Enrollment

1,350 estimated patients

Sex

All

Ages

18+ years old

Volunteers

No Healthy Volunteers

Inclusion and exclusion criteria

Inclusion Criteria (Fulfill 1,2,3 or 1,4):

Age ≥ 18 years;
Diabetes mellitus;
Three-vessel coronary artery disease (≥70% stenosis in the left anterior descending artery, circumflex artery, and right coronary artery system);
Patients who required heart team discussion judging by the interventional cardiologist.

Exclusion Criteria:

Prior PCI or CABG;
Acute myocardial infarction with ECG and biomarker tests indicating acute phase;
Concurrent severe valvular heart disease, large vessel disease, or giant ventricular aneurysm requiring surgical intervention;
Concurrent atrial fibrillation or severe arrhythmia;
Other emergency admissions where elective revascularization is contraindicated;
Refusal or rejection of a specific treatment options (PCI or CABG);
Refusal to participate in the study.