Electrophysiological Characteristics and Anatomical Differentiation of Epileptic and Non-epileptic Myoclonus.

Mansoura University Hospital

Status: Completed

Conditions: Evoked Potential; Myoclonus

Treatments: Diagnostic Test: Somatosensory evoked potential

Study type: Observational

Funder types: Other

Identifiers

NCT04235452

Mansoura University 11

Details and patient eligibility

About

This study was conducted on a series of patients with myoclonus to identify the electrophysiological characteristics and the anatomical classification of myoclonus of different causes.

Full description

The current study included 50 patients with different types of myoclonus in comparison to 30 control subjects. Electrophysiological study was done for all patients by Somatosensory Evoked Potential (SSEP) and Electroencephalography (EEG) while the control group underwent SSEP. SSEP was studied in the patients and control group by stimulation of right and left median nerves.

Enrollment: 50 patients

Sex: All

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• Myoclonus classified into primary and secondary myoclonus.

Exclusion criteria

• Psychiatric comorbidity to exclude psychological myoclonus.

Trial design

50 participants in 2 patient groups

Epileptic myoclonus

Description:

Juvenile Myoclonic Epilepsy and Progressive Myoclonic Epilepsy

Treatment:

Diagnostic Test: Somatosensory evoked potential

Non-epileptic myoclonus (secondary)

Description:

Post hypoxic myoclonus, Post ischemic stroke myoclonus, Hepatic, Chronic kidney disease, and Drug induced myoclonus

Treatment:

Diagnostic Test: Somatosensory evoked potential