Elevated Lipoprotein(a) in Hospital Staff (LPACO)

Changi General Hospital

Status: Enrolling

Conditions: Lipoprotein Types--Lp System Lp(A) Hyperlipoproteinemia; Hypercholesterolemia; Cardiovascular Diseases

Study type: Observational

Funder types: Other

Identifiers

NCT06304415

CIRB2023/2651

Details and patient eligibility

About

The objective of this study is to investigate the prevalence of elevated Lp(a) in the working general population.

Full description

The objective of this study is to investigate the prevalence of elevated lipoprotein(a) concentrations and distribution of lipoprotein(a) in a working general population. This is a prospective study investigating the association of lipoprotein(a) with cardiovascular markers and outcomes.

Enrollment: 2,800 estimated patients

Sex: All

Ages: 21 to 100 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

1. Any healthcare workers working in healthcare settings (regardless of PHI and/or private setting) aged 21 and above OR family member such as father, mother, siblings, grandparents, spouse and children aged 12 and above of recruited staff with high Lpa ≥120nmol/l
2. Study team members can also be recruited because we are trying to find the prevalence of elevated Lp(a)

Exclusion criteria

1. Inability to provide informed consent.
2. Pregnant women.
3. Prisoner

Trial design

2,800 participants in 1 patient group

Working General Population

Description:

Consenting hospital staff are recruited to this study. Blood test and questionnaires are taken at baseline. Prospective follow-up of cardiovascular events are undertaken.