Elevated Platelet Count as Prognostic Factor in Colorectal Cancer With Synchronous Liver Metastases (PLTCRC)

Integrated University Hospital Trust of Verona

Status: Completed

Conditions: Colorectal Carcinoma; Stage IV Colon Cancer; Colorectal Cancer

Treatments: Diagnostic Test: Measurement of platelet count at diagnosis

Study type: Observational

Funder types: Other

Identifiers

NCT03717519

CHIR CR

Details and patient eligibility

About

Colorectal cancer (CRC) is the third most common malignancy worldwide and is often metastatic at diagnosis. Despite progresses in surgical techniques and the introduction of novel chemotherapy regimens, many patients still suffer from a poor prognosis. It is therefore of utmost importance to identify prognostic markers that may improve selection of patients.

In recent years several studies demonstrated that preoperative blood tests as platelet count or neuthophil-to-lymphocyte ratio could be prognostic factors in CRC as well as other malignancies. The aim of this study was to evaluate the role of preoperative platelet count (PC) in patients with synchronous colorectal liver metastases.

Enrollment: 196 patients

Sex: All

Ages: 18 to 100 years old

Volunteers: No Healthy Volunteers

Inclusion criteria

• Colorectal cancer with synchronous liver metastases
• Possibility to retrieve pre-operative platelet count
• Age of 18 years or older
• Availabilty of clinical-pathological data
• Minimum follow up of 12 months

Exclusion criteria

• None

Trial design

196 participants in 1 patient group

s-CRLM

Description:

Patients with synchronous colorectal liver metastases who underwent surgical resection

Treatment:

Diagnostic Test: Measurement of platelet count at diagnosis