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Elongation of Foveal Tissue After Macular Hole Surgery

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Samsung Medical Center

Status

Completed

Conditions

Macular Holes

Treatments

Procedure: pars plana vitrectomy and fluid gas exchange

Study type

Interventional

Funder types

Other

Identifiers

NCT01471912
2011-10-003

Details and patient eligibility

About

In our experience, elongation of foveal tissue after macular hole surgery which was undetectable by conventional time-domain optical coherence tomography was often observed on spectral-domain optical coherence tomography images. Elongation of tissues inevitably induces some degree of disorganization of tissue microstructure.

The purpose of the present study was to evaluate elongation profile of foveal tissue after macular hole surgery and to investigate its impact on visual acuity and metamorphopsia.

Enrollment

31 patients

Sex

All

Ages

30 to 75 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • Patients who were diagnosed with idiopathic macular hole

Exclusion criteria

  • traumatic macular hole
  • evidence of ocular inflammation, diabetic retinopathy, hypertensive retinopathy, and retinal vasculitis, media opacity that would influence visual acuity or preclude acquisition of clear spectral domain optical coherence tomography images
  • presence of cataract judged to affect visual function, -6.0 diopters or more of spherical equivalent, prominent staphyloma
  • history of intraocular surgery other than uncomplicated cataract surgery, other ocular diseases that may influence the macular microstructure or visual function
  • patients with indistinct intraretinal structure on spectral domain optical coherence tomography images

Trial design

Primary purpose

Diagnostic

Allocation

N/A

Interventional model

Single Group Assignment

Masking

None (Open label)

Trial contacts and locations

1

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Data sourced from clinicaltrials.gov

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