Embryo Development Using Two Commercial Single-step Media

Eugonia

Status: Completed

Conditions: Infertility

Treatments: Other: embryo culture in different single-step media

Study type: Interventional

Funder types: Other

Identifiers

NCT02302638

Sage vs CSCM

Details and patient eligibility

About

This prospective study with sibling oocytes will evaluate the efficiency of two commercial single-step media, namely Sage 1-step and Continuous Single Culture Medium (CSCM), in terms of embryo utilization rates, blastocyst formation rates, embryo quality and pregnancy rates. Embryos will be cultured continuously for up to 6 days under identical conditions.

Enrollment: 43 patients

Sex: Female

Ages: 18 to 40 years old

Volunteers: Accepts Healthy Volunteers

Inclusion criteria

• at least 10 oocytes retrieved

Exclusion criteria

• frozen oocytes
• testicular biopsy
• less than 10 oocytes retrieved
• older than 40 years

Trial design

Primary purpose: Treatment

Allocation: Randomized

Interventional model: Parallel Assignment

Masking: Quadruple Blind

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43 participants in 2 patient groups

Sage 1-step

Active Comparator group

Description:

Embryo culture in different single-step media: Half of each patient's oocytes will be randomly allocated to be cultured in Sage 1-step medium for up to six days following oocyte retrieval.

Treatment:

Other: embryo culture in different single-step media

CSCM

Active Comparator group

Description:

Embryo culture in different single-step media: Half of each patient's oocytes will be randomly allocated to be cultured in CSC medium for up to six days following oocyte retrieval.

Treatment:

Other: embryo culture in different single-step media