ClinicalTrials.Veeva

Menu

Embryo Implantation After Induced Endometrial Injury

I

Instituto Valenciano de Infertilidad, IVI VALENCIA

Status

Completed

Conditions

Sterility

Treatments

Procedure: Scratching

Study type

Interventional

Funder types

Other

Identifiers

NCT01955356
1306-C-119-CV/IVI Valencia

Details and patient eligibility

About

Some studies have revealed that an induced endometrial injury could improve embryo human implantation in patients with implantation failure.

The purpose of this study is to determine whether the induced endometrial injury could be beneficial for regular patients undergoing IVF

Full description

Endometrial induced injury has been suggested that could improve embryo implantation in cases of patients with recurrent implantation failure. The mechanisms that induce that improvement remain unknown.

We want to analyse if the endometrial induce injury could be useful in cases of standard patients who require assisted reproductive techniques.

For that purpose we will start a randomized controlled trial with the ideal background in implantation in ART, the egg donation programme.

Enrollment

600 patients

Sex

Female

Ages

19 to 44 years old

Volunteers

No Healthy Volunteers

Inclusion criteria

  • 19-44 aged women
  • 19-29.9 Kg/m2.
  • 1st or 2nd fresh embryo transfer ( egg donation).
  • 1 or 2 blastocysts available.
  • written agreement.
  • > or = 6 mms endometrial thickness.

Exclusion criteria

  • Premature ovarian failure.
  • Endometrial pathology.
  • Insufficient endometrial development.
  • Hydrosalpinx
  • Mullerian malformations.

Trial design

Primary purpose

Treatment

Allocation

Randomized

Interventional model

Parallel Assignment

Masking

None (Open label)

600 participants in 2 patient groups

Scratching
Experimental group
Description:
induced endometrial injury
Treatment:
Procedure: Scratching
No scratching
No Intervention group
Description:
None intervention

Trial contacts and locations

1

Loading...

Data sourced from clinicaltrials.gov

Clinical trials

Find clinical trialsTrials by location
© Copyright 2025 Veeva Systems